Expression of the polycomb group gene bmi-1 in the early chick embryo.

Journal article

Bmi-1 is a protooncogene of the polycomb group that has important functions in self-renewal of adult stem cells and maintenance of anterior identity along the embryonic body axis. Despite these important functions, surprisingly little is known about its distribution pattern in the embryo. Here, we have isolated the chick homologue of bmi-1 and examined its expression pattern from gastrulation through neurulation and establishment of organ rudiments. During gastrulation, bmi-1 transcripts were...

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Authors: Fraser, P; Sauka-Spengler, T

• Journal: Gene expression patterns : GEP
• Volume: 5
• Issue: 1
• Pages: 23-27
• Publication date: 2004-11-01
• DOI: 10.1016/j.modgep.2004.06.011
• EISSN: 1872-7298
• ISSN: 1567-133X
• Language: English
• Keywords: Gene Expression Profiling; Reverse Transcriptase Polymerase Chain Reaction; Multipotent Stem Cells; Amino Acid Sequence; Animals; Proto-Oncogene Proteins; Central Nervous System; In Situ Hybridization; Chick Embryo; Molecular Sequence Data