Journal article icon

Journal article

Identification of antigen-specific B cell receptor sequences using public repertoire analysis.

Abstract:

High-throughput sequencing allows detailed study of the BCR repertoire postimmunization, but it remains unclear to what extent the de novo identification of Ag-specific sequences from the total BCR repertoire is possible. A conjugate vaccine containing Haemophilus influenzae type b (Hib) and group C meningococcal polysaccharides, as well as tetanus toxoid (TT), was used to investigate the BCR repertoire of adult humans following immunization and to test the hypothesis that public or convergen...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Publisher copy:
10.4049/jimmunol.1401405

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Paediatrics
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Paediatrics
Role:
Author
Expand authors...
More from this funder
Funding agency for:
Trück, J
More from this funder
Funding agency for:
Lunter, G
More from this funder
Funding agency for:
Pollard, AJ
More from this funder
Funding agency for:
Pollard, AJ
Expand funders...
Publisher:
American Association of Immunologists Publisher's website
Journal:
Journal of immunology (Baltimore, Md. : 1950) Journal website
Volume:
194
Issue:
1
Pages:
252-261
Publication date:
2015-01-01
DOI:
EISSN:
1550-6606
ISSN:
0022-1767
URN:
uuid:4e845cb8-dcc5-488b-8ab1-8ff7828e6c30
Source identifiers:
489763
Local pid:
pubs:489763
Language:
English

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP