- Abstract:
-
High-throughput sequencing allows detailed study of the BCR repertoire postimmunization, but it remains unclear to what extent the de novo identification of Ag-specific sequences from the total BCR repertoire is possible. A conjugate vaccine containing Haemophilus influenzae type b (Hib) and group C meningococcal polysaccharides, as well as tetanus toxoid (TT), was used to investigate the BCR repertoire of adult humans following immunization and to test the hypothesis that public or convergen...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Publisher copy:
- 10.4049/jimmunol.1401405
-
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- Funding agency for:
- Trück, J
- Publisher:
- American Association of Immunologists Publisher's website
- Journal:
- Journal of immunology (Baltimore, Md. : 1950) Journal website
- Volume:
- 194
- Issue:
- 1
- Pages:
- 252-261
- Publication date:
- 2015-01-01
- DOI:
- EISSN:
-
1550-6606
- ISSN:
-
0022-1767
- URN:
-
uuid:4e845cb8-dcc5-488b-8ab1-8ff7828e6c30
- Source identifiers:
-
489763
- Local pid:
- pubs:489763
- Language:
- English
- Copyright holder:
- American Association of Immunologists, Inc.
- Copyright date:
- 2015
- Notes:
- Copyright © 2014 by The American Association of Immunologists, Inc.
Journal article
Identification of antigen-specific B cell receptor sequences using public repertoire analysis.
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