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Journal article

Gut feeling about alpha-synuclein in gastro-intestinal biopsies: biomarker in the making?

Abstract:

In recent years, several studies have investigated the potential of immunohistochemical detection of -synuclein in the gastro-intestinal tract to diagnose Parkinson’s disease (PD). While methodological heterogeneity has hindered comparability between studies, it has become increasingly apparent that the high sensitivity and specificity reported in preliminary studies has not been sustained in subsequent large scale studies. What constitutes pathological -synuclein in the alimentary canal th...

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Publication status:
Accepted
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
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Funding agency for:
Parkkinen, L
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Funding agency for:
Parkkinen, L
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Funding agency for:
Parkkinen, L
Publisher:
Wiley
Journal:
Movement Disorders More from this journal
Publication date:
2015-01-01
ISSN:
1531-8257
Keywords:
Pubs id:
pubs:577774
UUID:
uuid:4e7bc2bc-84a3-41fa-8984-5fcc4fcd5473
Local pid:
pubs:577774
Source identifiers:
577774
Deposit date:
2015-12-03

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