Journal article
Integration of 3D-printed cerebral cortical tissue into an ex vivo lesioned brain slice
- Abstract:
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Engineering human tissue with diverse cell types and architectures remains challenging. The cerebral cortex, which has a layered cellular architecture composed of layer-specific neurons organised into vertical columns, delivers higher cognition through intricately wired neural circuits. However, current tissue engineering approaches cannot produce such structures. Here, we use a droplet printing technique to fabricate tissues comprising simplified cerebral cortical columns. Human induced p...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Version of record, pdf, 8.3MB, Terms of use)
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- Publisher copy:
- 10.1038/s41467-023-41356-w
Authors
Bibliographic Details
- Publisher:
- Springer Nature
- Journal:
- Nature Communications More from this journal
- Volume:
- 14
- Issue:
- 1
- Article number:
- 5986
- Publication date:
- 2023-10-04
- Acceptance date:
- 2023-09-01
- DOI:
- EISSN:
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2041-1723
- Pmid:
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37794031
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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1543969
- Local pid:
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pubs:1543969
- Deposit date:
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2024-02-26
Terms of use
- Copyright holder:
- Jin et al.
- Copyright date:
- 2023
- Rights statement:
- Copyright © 2023, The Author(s). This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
- Licence:
- CC Attribution (CC BY)
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