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Journal article

White matter lesion progression, brain atrophy, and cognitive decline: the Austrian stroke prevention study.

Abstract:

White matter lesions progress over time, but the clinical consequences are widely unknown. Three-hundred twenty-nine elderly community-dwelling volunteers underwent serial magnetic resonance imaging scanning and cognitive testing at baseline and at 3- and 6-year follow-up. We measured the changes in white matter lesion and brain parenchymal volumes. After 6 years, the median increase in white matter lesion load was 0.2 cm3 (interquartile range [IQR], 0.0-0.80 cm3) with a maximum of 31.4 cm3. ...

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Publication status:
Published

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Publisher copy:
10.1002/ana.20630

Authors


Schmidt, R More by this author
Enzinger, C More by this author
Petrovic, K More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
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Journal:
Annals of neurology
Volume:
58
Issue:
4
Pages:
610-616
Publication date:
2005-10-05
DOI:
EISSN:
1531-8249
ISSN:
0364-5134
URN:
uuid:4e489f7f-44e0-47ca-9f1a-f0c5303cb005
Source identifiers:
116471
Local pid:
pubs:116471

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