Journal article
Activation of CCR2+ human proinflammatory monocytes by human herpesvirus-6B chemokine N-terminal peptide.
- Abstract:
-
Human monocytes expressing CCR2 with CD14 and CD16 can mediate antigen presentation, and promote inflammation, brain infiltration and immunosenescence. Recently identified roles are in human immunodeficiency virus infection, tuberculosis and parasitic disease. Human herpesvirus 6B (HHV-6B) encodes a chemokine, U83B, which is monospecific for CCR2, and is distinct from the related HHV-6A U83A, which activates CCR1, CCR4, CCR5, CCR6 and CCR8 on immune effector cells and dendritic cells. These d...
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Bibliographic Details
- Journal:
- Journal of general virology
- Volume:
- 94
- Issue:
- Pt 7
- Pages:
- 1624-1635
- Publication date:
- 2013-07-01
- DOI:
- EISSN:
-
1465-2099
- ISSN:
-
0022-1317
- Source identifiers:
-
390837
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:390837
- UUID:
-
uuid:4e393f7c-e391-4559-937c-df3944770e81
- Local pid:
- pubs:390837
- Deposit date:
- 2013-11-17
Terms of use
- Copyright date:
- 2013
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