The intense airway inflammatory response associated with respiratory syncytial virus (RSV) infection may be an important determinant in the severity of the disease. Interleukin (IL)-10 is a key regulatory cytokine known to be secreted during this infection. We investigated the role that IL-10 plays in RSV disease by studying the effects that variation in the IL10 gene has on the outcome of the disease. Eight single nucleotide polymorphisms (SNPs) spanning the IL10 gene were selected, and hapl...Expand abstract
- Publication status:
- Publisher copy:
- Copyright date:
Genetic variation at the IL10 gene locus is associated with severity of respiratory syncytial virus bronchiolitis.
Views and Downloads
If you are the owner of this record, you can report an update to it here: Report update to this record