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1H-MR spectroscopy for analysis of cardiac lipid and creatine metabolism

Abstract:

Magnetic resonance spectroscopy (MRS) is the only non-invasive, non-radiation-based technique for investigating the metabolism of living tissue. MRS of protons (1H-MRS), which provides the highest sensitivity of all MR-visible nuclei, is a method capable of detecting and quantifying specific cardiac biomolecules, such as lipids and creatine in normal and diseased hearts in both animal models and humans. This can be used to study mechanisms of heart failure development in a longitudinal manner...

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Publisher copy:
10.1007/s10741-012-9341-z

Authors


Faller, KME More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Cardiovascular Medicine, BHF Centre of Research Excellence
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Cardiovascular Medicine, BHF Centre of Research Excellence
Schneider, JE More by this author
Journal:
Heart Failure Reviews
Volume:
18
Issue:
5
Pages:
657-668
Publication date:
2013-09-05
DOI:
EISSN:
1573-7322
ISSN:
1382-4147
URN:
uuid:4e0f929f-b74e-4cda-80a8-21f625849310
Source identifiers:
435142
Local pid:
pubs:435142

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