- Abstract:
-
In order for site-directed polymer ultrasound contrast agents (UCAs) to provide acoustic enhancement at disease sites to distinguish normal tissue from diseased tissue, the surface of these agents must be functionalized with mixtures of grafted polymers. Here a combination of longer liganded polyethylene glycol (PEG)-lipids and shorter unliganded PEG-lipids were introduced into the oil phase of a modified solvent evaporation double emulsion method for preparing UCAs. UCAs with different lengt...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1002/bit.22678
-
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- Journal:
- Biotechnology and bioengineering
- Volume:
- 106
- Issue:
- 3
- Pages:
- 501-506
- Publication date:
- 2010-06-05
- DOI:
- EISSN:
-
1097-0290
- ISSN:
-
0006-3592
- URN:
-
uuid:4df587ac-3772-41d1-b883-54d1c70f2942
- Source identifiers:
-
327705
- Local pid:
- pubs:327705
- Language:
- English
- Keywords:
- Copyright date:
- 2010
Journal article
Targeted binding of PEG-lipid modified polymer ultrasound contrast agents with tiered surface architecture.
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