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Heterogeneity among estimates of the core genome and pan-genome in different pneumococcal populations

Abstract:

Background: Understanding the structure of a bacterial population is essential in order to understand bacterial evolution, or which genetic lineages cause disease, or the consequences of perturbations to the bacterial population. Estimating the core genome, the genes common to all or nearly all strains of a species, is an essential component of such analyses. The size and composition of the core genome varies by dataset, but our hypothesis was that variation between different collections of t...

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Publication status:
Submitted

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Publisher copy:
10.1101/133991

Authors


Van Tonder, A More by this author
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Institution:
University of Oxford
Division:
MPLS Division
Department:
Zoology
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Institution:
University of Oxford
Division:
MPLS Division
Department:
Zoology
ORCID:
0000-0002-0751-0287
Haraldsson, G More by this author
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Journal:
bioRxiv
Publication date:
2017-05-06
DOI:
Pubs id:
pubs:896596
URN:
uri:4d96e5e9-3391-4f7f-ad36-061c46f6d5a8
UUID:
uuid:4d96e5e9-3391-4f7f-ad36-061c46f6d5a8
Local pid:
pubs:896596
Keywords:

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