Journal article
Chromosomal mapping of genetic loci associated with non-insulin dependent diabetes in the GK rat.
- Abstract:
-
Goto-Kakizaki (GK) rats are a well characterized model for non-insulin dependent diabetes mellitus (NIDDM). We have used a combination of physiological and genetic studies to identify quantitative trait loci (QTLs) responsible for the control of glucose homeostasis and insulin secretion in a F2 cohort bred from spontaneously diabetic GK rats. The genetic dissection of NIDDM allowed us to map up to six independently segregating loci predisposing to hyperglycaemia, glucose intolerance or altere...
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- Publication status:
- Published
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- Publisher copy:
- 10.1038/ng0196-38
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Authors
Bibliographic Details
- Journal:
- Nature genetics
- Volume:
- 12
- Issue:
- 1
- Pages:
- 38-43
- Publication date:
- 1996-01-01
- DOI:
- EISSN:
-
1546-1718
- ISSN:
-
1061-4036
- Source identifiers:
-
7695
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:7695
- UUID:
-
uuid:4d8abbc0-4655-47f6-a0af-a6d48b8d824a
- Local pid:
- pubs:7695
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 1996
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