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Journal article

Immunohistologic demonstration of abnormal colonic crypt cell kinetics in ulcerative colitis.

Abstract:

A monoclonal antibody, Ki-67, that reacts with cells in the proliferative phases (G1, G2, S, and M) of the cell cycle was used in an immunohistochemical labeling reaction to examine the colonic crypt epithelium in active ulcerative colitis, inactive ulcerative colitis, and normal mucosa. The proportions of labeled cells in the lower two thirds (proliferative zone) and in the upper quarter of the crypt were determined. The proportions of Ki-67-positive crypt epithelial cells in both the prolif...

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Publication status:
Published

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Authors


Franklin, WA More by this author
McDonald, GB More by this author
Gatter, KC More by this author
Jewell, DP More by this author
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Journal:
Human pathology
Volume:
16
Issue:
11
Pages:
1129-1132
Publication date:
1985-11-05
DOI:
EISSN:
1532-8392
ISSN:
0046-8177
URN:
uuid:4d7efbd7-8205-4b4b-a2ec-69a1a01a142b
Source identifiers:
135886
Local pid:
pubs:135886

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