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Journal article

Molecular genetics of colon cancer.

Abstract:

Colorectal cancer remains a major health problem. Few therapies are effective apart from surgery, and survival has increased little in recent years. This is despite the fact that screening by colonoscopy can potentially remove nearly all colorectal tumours before they become malignant. Molecular genetics has identified some inherited mutations (such as at APC and the mismatch repair loci) that predispose to colon cancer and some somatic mutations (such as at APC and p53) that cause sporadic c...

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Publication status:
Published

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Publisher copy:
10.1023/a:1005744323215

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Novelli, M More by this author
Journal:
Cancer metastasis reviews
Volume:
16
Issue:
1-2
Pages:
67-79
Publication date:
1997-06-05
DOI:
EISSN:
1573-7233
ISSN:
0167-7659
URN:
uuid:4d67139e-5699-42be-a57b-3ee01027e3a2
Source identifiers:
45509
Local pid:
pubs:45509

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