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Amphioxus and ascidian Dmbx homeobox genes give clues to the vertebrate origins of midbrain development.

Abstract:

The ancestral chordate neural tube had a tripartite structure, comprising anterior, midbrain-hindbrain boundary (MHB) and posterior regions. The most anterior region encompasses both forebrain and midbrain in vertebrates. It is not clear when or how the distinction between these two functionally and developmentally distinct regions arose in evolution. Recently, we reported a mouse PRD-class homeobox gene, Dmbx1, expressed in the presumptive midbrain at early developmental stages, and the hind...

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Publication status:
Published

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Publisher copy:
10.1242/dev.01201

Authors


Takahashi, T More by this author
Holland, PW More by this author
Journal:
Development (Cambridge, England)
Volume:
131
Issue:
14
Pages:
3285-3294
Publication date:
2004-07-05
DOI:
EISSN:
1477-9129
ISSN:
0950-1991
URN:
uuid:4d55e2a8-522f-424b-8bad-4078d4427e5b
Source identifiers:
204413
Local pid:
pubs:204413

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