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Journal article

Overlapping CNS inflammatory diseases: differentiating features of NMO and MS.

Abstract:

Neuromyelitis optica (NMO) has long been considered as a variant of multiple sclerosis (MS) rather than a distinct disease. This concept changed with the discovery of serum antibodies (Ab) against aquaporin-4 (AQP4), which unequivocally differentiate NMO from MS. Patients who test positive for AQP4-Abs and present with optic neuritis (ON) and transverse myelitis (TM) are diagnosed with NMO and those who show an incomplete phenotype with isolated ON or longitudinally extensive TM (LETM) or les...

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Publication status:
Published

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Publisher copy:
10.1136/jnnp-2014-308984

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
Publisher:
BMJ Publishing Group
Journal:
Journal of neurology, neurosurgery, and psychiatry
Volume:
86
Issue:
1
Pages:
20-25
Publication date:
2015-01-05
DOI:
EISSN:
1468-330X
ISSN:
0022-3050
URN:
uuid:4d490fff-730c-4d0c-ad3b-e826a5686f16
Source identifiers:
485467
Local pid:
pubs:485467
Language:
English
Keywords:

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