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Journal article

An in-depth analysis of original antigenic sin in dengue virus infection.

Abstract:

The evolution of dengue viruses has resulted in four antigenically similar yet distinct serotypes. Infection with one serotype likely elicits lifelong immunity to that serotype, but generally not against the other three. Secondary or sequential infections are common, as multiple viral serotypes frequently cocirculate. Dengue infection, although frequently mild, can lead to dengue hemorrhagic fever (DHF) which can be life threatening. DHF is more common in secondary dengue infections, implying...

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Publication status:
Published

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Publisher copy:
10.1128/jvi.01826-10

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Journal:
Journal of virology
Volume:
85
Issue:
1
Pages:
410-421
Publication date:
2011-01-05
DOI:
EISSN:
1098-5514
ISSN:
0022-538X
URN:
uuid:4d2ea2e4-9a98-4a2f-acfc-8dcb1106fec3
Source identifiers:
90831
Local pid:
pubs:90831

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