- Abstract:
-
Base excision repair (BER) is the major pathway for the repair of simple, non-bulky lesions in DNA that is initiated by a damage-specific DNA glycosylase. Several human DNA glycosylases exist that efficiently excise numerous types of lesions, although the close proximity of a single strand break (SSB) to a DNA adduct can have a profound effect on both BER and SSB repair. We recently reported that DNA lesions located as a second nucleotide 5'-upstream to a DNA SSB are resistant to DNA glycosyl...
Expand abstract - Publication status:
- Published
- Journal:
- Nucleic acids research
- Volume:
- 35
- Issue:
- 4
- Pages:
- 1054-1063
- Publication date:
- 2007
- DOI:
- EISSN:
-
1362-4962
- ISSN:
-
0305-1048
- URN:
-
uuid:4d153164-e9d8-479c-adf6-3e36b1c81b16
- Source identifiers:
-
131160
- Local pid:
- pubs:131160
- Copyright date:
- 2007
Journal article
DNA polymerase delta-dependent repair of DNA single strand breaks containing 3'-end proximal lesions.
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