- Abstract:
-
Most eukaryotic genomes contain large regions of satellite DNA. These arrays are often associated with essential chromosomal functions, but remain largely absent from genome projects because of difficulties in cloning and sequence assembly. The numerous small chromosomes of the parasite Trypanosoma brucei fall into this category, yet are critical to understanding the genome because of their role in antigenic variation. Their relatively small size, however, makes them particularly amenable to ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1101/gr.2227704
-
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- Journal:
- Genome research
- Volume:
- 14
- Issue:
- 6
- Pages:
- 1014-1024
- Publication date:
- 2004-06-05
- DOI:
- EISSN:
-
1549-5469
- ISSN:
-
1088-9051
- URN:
-
uuid:4d0ad2f1-874d-4024-aec1-035fda47d47b
- Source identifiers:
-
16867
- Local pid:
- pubs:16867
- Copyright date:
- 2004
Journal article
The small chromosomes of Trypanosoma brucei involved in antigenic variation are constructed around repetitive palindromes.
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