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Comparative efficacy of drugs for treating giardiasis: a systematic update of the literature and network meta-analysis of randomized clinical trials

Abstract:

Background: Giardiasis is the commonest intestinal protozoal infection worldwide. The current first-choice therapy is metronidazole. Recently, other drugs with potentially higher efficacy or with fewer and milder side effects have increased in popularity, but evidence is limited by a scarcity of randomized controlled trials (RCTs) comparing the many treatment options available. Network meta-analysis (NMA) is a useful tool to compare multiple treatments when there is limited or no direct evide...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1093/jac/dkx430

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Primary Care; Primary Care Health Sciences
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Primary Care; Primary Care Health Sciences
Publisher:
Oxford University Press Publisher's website
Journal:
Journal of Antimicrobial Chemotherapy Journal website
Volume:
73
Issue:
3
Pages:
596–606
Publication date:
2017-11-27
Acceptance date:
2017-10-12
DOI:
EISSN:
1460-2091
ISSN:
0305-7453
Pubs id:
pubs:740635
URN:
uri:4d067092-1996-4b90-94c6-77d0ad2a36b3
UUID:
uuid:4d067092-1996-4b90-94c6-77d0ad2a36b3
Local pid:
pubs:740635
Language:
English

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