Journal article icon

Journal article

Improved high-performance liquid chromatographic analysis of terazosin in human plasma.

Abstract:

A simple, sensitive and reproducible high-performance liquid chromatography (HPLC) method was developed for the determination of terazosin in human plasma. The method involves a one-step single solvent extraction procedure using dichloromethane with a 0.25 ml plasma sample. Recovery values were all greater than 90% over the concentration range 0.25-100 ng/ml. Terazosin was found to adsorb to glass or plastic tubes, but this could be circumvented by using disposable plastic tubes. Also, rinsin...

Expand abstract

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Journal:
Journal of chromatography. B, Biomedical sciences and applications
Volume:
745
Issue:
2
Pages:
439-443
Publication date:
2000-08-05
DOI:
ISSN:
1387-2273
URN:
uuid:4cffd8ca-71a3-4ec9-9c03-6bd9dd77a2b7
Source identifiers:
134136
Local pid:
pubs:134136

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP