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Journal article

Antagonism of microRNA function in zebrafish embryos by using locked nucleic acid enzymes (LNAzymes).

Abstract:

MicroRNAs (miRNAs) have crucial functions in many cellular processes, such as differentiation, proliferation and apoptosis; aberrant expression of miRNAs has been linked to human diseases, including cancer. Tools that allow specific and efficient knockdown of miRNAs would be of immense importance for exploring miRNA function. Zebrafish serves as an excellent vertebrate model system to understand the functions of miRNAs involved in a variety of biological processes. We designed and employed a ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/cbic.201100789

Authors


Suryawanshi, H More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Ramasamy, S More by this author
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Publisher:
WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim Publisher's website
Journal:
Chembiochem : a European journal of chemical biology Journal website
Volume:
13
Issue:
4
Pages:
584-589
Publication date:
2012-03-05
DOI:
EISSN:
1439-7633
ISSN:
1439-4227
URN:
uuid:4cfe9f7b-d305-47f1-b0d9-30e272d4fc72
Source identifiers:
472435
Local pid:
pubs:472435

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