MicroRNAs (miRNAs) have crucial functions in many cellular processes, such as differentiation, proliferation and apoptosis; aberrant expression of miRNAs has been linked to human diseases, including cancer. Tools that allow specific and efficient knockdown of miRNAs would be of immense importance for exploring miRNA function. Zebrafish serves as an excellent vertebrate model system to understand the functions of miRNAs involved in a variety of biological processes. We designed and employed a ...Expand abstract
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- WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim Publisher's website
- Chembiochem : a European journal of chemical biology Journal website
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- WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim
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- © 2012 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim. The full text of this article is not available in ORA.
Antagonism of microRNA function in zebrafish embryos by using locked nucleic acid enzymes (LNAzymes).
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