Journal article
Identification of a class of protein ADP-ribosylating sirtuins in microbial pathogens
- Abstract:
-
Sirtuins are a diverse enzyme family of NAD+-dependent protein deacylases that control a variety of cellular processes including cell cycle progression, maintenance of genome integrity, and metabolic homeostasis (Asher and Schibler, 2011, Choi and Mostoslavsky, 2014). The overall structure of sirtuins is comprised of a highly conserved Rossmann fold and a more diverse zinc coordinating domain (Yuan and Marmorstein, 2012). The reaction mechanism is initialized by activation of NAD+, followed b...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Preview, Version of record, pdf, 2.9MB, Terms of use)
-
- Publisher copy:
- 10.1016/j.molcel.2015.06.013
Authors
Bibliographic Details
- Publisher:
- Cell Press
- Journal:
- Molecular cell More from this journal
- Volume:
- 59
- Issue:
- 2
- Pages:
- 309-320
- Publication date:
- 2015-07-09
- Acceptance date:
- 2015-06-04
- DOI:
- EISSN:
-
1097-4164
- ISSN:
-
1097-2765
- Pmid:
-
26166706
Item Description
- Language:
-
English
- Keywords:
-
- Pubs id:
-
pubs:536109
- UUID:
-
uuid:4cd5fefe-079f-4513-8774-08cda7e466cc
- Local pid:
-
pubs:536109
- Source identifiers:
-
536109
- Deposit date:
-
2016-12-13
Terms of use
- Copyright holder:
- Rack, JG et al
- Copyright date:
- 2015
- Notes:
- © 2015 The Authors This is an open access article under the CC BY license http://creativecommons.org/licenses/by/4.0/
- Licence:
- CC Attribution (CC BY)
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record