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Journal article

Neither sequence variation in the IL-10 gene promoter nor presence of IL-10 protein in the cerebral cortex is associated with Alzheimer's disease.

Abstract:

Interleukin 10 (IL-10) is an important anti-inflammatory cytokine produced in response to neuroinflammation and might be involved in modulating the progression of Alzheimer's disease (AD) through inhibiting the action of pro-inflammatory cytokines. We have used immunohistochemistry, Western blotting, real time-PCR (RT-PCR) on frontal (BA 6/24) and temporal (BA 20-22) neocortex and hippocampus from AD and control brains as well as genetic association analysis to address the possible involvemen...

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Publication status:
Published

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Journal:
Neuroscience letters
Volume:
408
Issue:
2
Pages:
141-145
Publication date:
2006-11-01
DOI:
EISSN:
1872-7972
ISSN:
0304-3940
Source identifiers:
33598
Language:
English
Keywords:
Pubs id:
pubs:33598
UUID:
uuid:4cc027b2-5b97-4ee7-8b94-563c479a45f7
Local pid:
pubs:33598
Deposit date:
2012-12-19

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