Journal article icon

Journal article

Viral particles drive rapid differentiation of memory B cells into secondary plasma cells producing increased levels of antibodies.

Abstract:

Extensive studies have been undertaken to describe naive B cells differentiating into memory B cells at a cellular and molecular level. However, relatively little is known about the fate of memory B cells upon Ag re-encounter. We have previously established a system based on virus-like particles (VLPs), which allows tracking of VLP-specific B cells by flow cytometry as well as histology. Using allotype markers, it is possible to adoptively transfer memory B cells into a naive mouse and track ...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.4049/jimmunol.1400065

Authors


Mohanan, D More by this author
Fettelschoss, A More by this author
Expand authors...
Publisher:
American Association of Immunologists
Journal:
Journal of immunology (Baltimore, Md. : 1950)
Volume:
192
Issue:
12
Pages:
5499-5508
Publication date:
2014-06-05
DOI:
EISSN:
1550-6606
ISSN:
0022-1767
URN:
uuid:4cbf8cb6-f5a4-48cd-ba3a-e2d3ed263829
Source identifiers:
465269
Local pid:
pubs:465269

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP