Family history of stroke does not predict risk of stroke after transient ischemic attack.
BACKGROUND AND PURPOSE: Animal models suggest a genetic contribution to cerebral susceptibility to ischemia. Family history of stroke (FHxstroke) is a risk factor for ischemic stroke, but there is significant confounding by heritability of hypertension and other intermediate phenotypes, and it is uncertain whether genetic factors have a direct independent influence on cerebral susceptibility to ischemia in man. METHODS: We related detailed FHxstroke to baseline characteristics and subsequent...Expand abstract
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