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Journal article

The epidermis as an adjuvant

Abstract:

It is now clear that the epidermis has an active role in local immune responses in the skin. Keratinocytes are involved early in inflammation by providing first-line innate mechanisms and, in addition, can contribute to adaptive immune responses that may be associated with clinical disease. Moreover, keratinocytes are capable of enhancing and shaping the outcome of inflammation in response to stimuli and promoting particular types of immune bias. Through understanding the underlying mechanism...

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Publisher copy:
10.1038/jid.2011.398

Authors


Gutowska-Owsiak, D More by this author
Journal:
Journal of Investigative Dermatology
Volume:
132
Issue:
3 PART 2
Pages:
940-948
Publication date:
2012-03-05
DOI:
EISSN:
1523-1747
ISSN:
0022-202X
URN:
uuid:4c8af56c-1ebf-4b5e-9b29-5e100db3713a
Source identifiers:
316758
Local pid:
pubs:316758
Language:
English

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