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Protocatechuic acid promotes cell proliferation and reduces basal apoptosis in cultured neural stem cells.

Abstract:

Protocatechuic acid (PCA), a phenolic compound isolated from the kernels of Alpinia oxyphylla, showed anti-oxidant neuroprotective property in our previous study. However, it is still unknown whether PCA have effects on the cultured neural stem cells (NSCs). In this study, we investigated the roles of PCA in the survival and apoptosis of rat NSCs under normal conditions. NSCs obtained from 13.5-day-old rat embryos were propagated as neurospheres and cultured under normal conditions with or wi...

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Publication status:
Published

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Publisher copy:
10.1016/j.tiv.2008.11.008

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Journal:
Toxicology in vitro : an international journal published in association with BIBRA
Volume:
23
Issue:
2
Pages:
201-208
Publication date:
2009-03-05
DOI:
EISSN:
1879-3177
ISSN:
0887-2333
URN:
uuid:4c88806f-8be0-48ad-be9c-b2ff2e32fc22
Source identifiers:
62095
Local pid:
pubs:62095

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