Journal article
Variants in ST8SIA1 do not play a major role in susceptibility to multiple sclerosis in Canadian families.
- Abstract:
-
Multiple sclerosis (MS) is a complex trait with a significant genetic component. Recent work has implicated the ST8SIA1 gene, encoding a ganglioside synthase, in susceptibility to the disease, perhaps with a parent-of-origin effect. In this investigation of 1318 MS patients from 756 Canadian families, we analysed the transmission of the four single nucleotide polymorphisms in ST8SIA previously shown to be associated with MS. No significant association was found in the entire sample or when st...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/j.jneuroim.2009.04.017
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Bibliographic Details
- Journal:
- Journal of neuroimmunology
- Volume:
- 212
- Issue:
- 1-2
- Pages:
- 142-144
- Publication date:
- 2009-07-05
- DOI:
- EISSN:
-
1872-8421
- ISSN:
-
0165-5728
- URN:
-
uuid:4c7fee71-6e69-4047-8bd4-0130b212b308
- Source identifiers:
-
34714
- Local pid:
- pubs:34714
Item Description
- Language:
- English
- Keywords:
Terms of use
- Copyright date:
- 2009
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