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The small FNR regulon of Neisseria gonorrhoeae: comparison with the larger Escherichia coli FNR regulon and interaction with the NarQ-NarP regulon

Abstract:

Background: Neisseria gonorrhoeae can survive during oxygen starvation by reducing nitrite to nitrous oxide catalysed by the nitrite and nitric oxide reductases, AniA and NorB. The oxygen-sensing transcription factor, FNR, is essential for transcription activation at the aniA promoter, and full activation also requires the two-component regulatory system, NarQ-NarP, and the presence of nitrite. The only other gene known to be activated by the gonococcal FNR is ccp encoding a cytochrome c pero...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/1471-2164-8-35

Authors


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Institution:
University of Birmingham, UK
Department:
School of Biosciences
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Institution:
University of Birmingham, UK
Department:
School of Biosciences
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Institution:
University of Oxford
Research group:
Bacterial Pathogenesis and Functional Genomics Group
Department:
Medical Sciences Division - Pathology
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Institution:
University of Oxford
Research group:
Computational Biology Research Group
Department:
Medical Sciences Division - Pathology
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Institution:
University of Birmingham, UK
Department:
The Medical School
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Funding agency for:
Rebekah N. Whitehead
EPA Cephalosporin Trust More from this funder
Publisher:
BioMed Central Publisher's website
Journal:
BMC Genomics Journal website
Volume:
8
Pages:
Article: 35
Publication date:
2007-01-05
DOI:
ISSN:
1471-2180
URN:
uuid:4c774d11-429b-497f-ad0d-2d3fa1b88155
Local pid:
ora:1781
Language:
English
Keywords:
Subjects:

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