- Abstract:
-
The adult mammalian kidney has a complex, highly-branched collecting duct epithelium that arises as a ureteric bud sidebranch from an epithelial tube known as the nephric duct. Subsequent branching of the ureteric bud to form the collecting duct tree is regulated by subcellular interactions between the epithelium and a population of mesenchymal cells that surround the tips of outgrowing branches. The mesenchymal cells produce glial cell-line derived neurotrophic factor (GDNF), that binds with...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 2.7mb)
-
- Publisher copy:
- 10.1007/s00285-018-1208-z
-
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- Publisher:
- Springer Publisher's website
- Journal:
- Journal of Mathematical Biology Journal website
- Volume:
- 76
- Issue:
- 7
- Pages:
- 1673-1697
- Publication date:
- 2018-02-01
- Acceptance date:
- 2018-01-02
- DOI:
- EISSN:
-
1432-1416
- ISSN:
-
0303-6812
- Pubs id:
-
pubs:823188
- URN:
-
uri:4c6c8698-7b78-4b43-8736-507009faef1d
- UUID:
-
uuid:4c6c8698-7b78-4b43-8736-507009faef1d
- Local pid:
- pubs:823188
- Language:
- English
- Keywords:
- Copyright holder:
- Byrne et al.
- Copyright date:
- 2018
- Notes:
- © The Author(s) 2018. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
Journal article
Bayesian inference of agent-based models: a tool for studying kidney branching morphogenesis
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