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How can we design better vaccines to prevent HIV infection in women?

Abstract:

The human immunodeficiency virus (HIV) burden in women continues to increase, and heterosexual contact is now the most common route of infection worldwide. Effective protection of women against HIV-1 infection may require a vaccine specifically targeting mucosal immune responses in the female genital tract (FGT). To achieve this goal, a much better understanding of the immunology of the FGT is needed. Here we review the architecture of the immune system of the FGT, recent studies of potential...

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Publication status:
Published

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Publisher copy:
10.3389/fmicb.2014.00572

Authors


Rafferty, H More by this author
Rowland-Jones, S More by this author
Publisher:
Frontiers Research Foundation
Journal:
Frontiers in microbiology
Volume:
5
Issue:
OCT
Pages:
572
Publication date:
2014
DOI:
EISSN:
1664-302X
ISSN:
1664-302X
URN:
uuid:4c69827e-525e-4b9a-b14f-575f81eff034
Source identifiers:
491966
Local pid:
pubs:491966
Language:
English
Keywords:

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