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Conference item

The transcriptional effects of thermal injury and cooling on human skin and implications for wound healing

Abstract:
Cooling has a key role in burns first aid, but no clear mechanism. We have developed an ethically-approved, validated in vivo human model for cooling of partial-thickness burns utilising bilateral areas of abdominal skin discarded during DIEP surgery. Aims To create cooled and uncooled burns and controls in volunteers, and sequence their RNA for transcriptional changes caused by burning and cooling.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/bjs.10864

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM; Weatherall Insti. of Molecular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
ORCID:
0000-0003-2780-7173
Publisher:
Wiley Publisher's website
Journal:
British Journal of Surgery Journal website
Host title:
Society of Academic and Research Surgery 2018 Annual Meeting (SARS 2018)
Publication date:
2018-03-07
DOI:
ISSN:
0007-1323 and 1365-2168
Source identifiers:
832037
Pubs id:
pubs:832037
UUID:
uuid:4c4810cc-cf4e-4271-9f64-e34ae0b4bb25
Local pid:
pubs:832037
Deposit date:
2018-05-11

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