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Thermodynamic Aspects of DNA Nanoconstruct Stability and Design

Abstract:

In the present study, we use the fluorescent DNA base analog tCå to investigate the thermal stability of a small DNA hexagon and the thermodynamie factors that govern the formation of such a structure. The DNA molecule is becoming increasingly popular as a material for bottom-up construction of nanostructures; however, relatively little attention has been given to the thermodynamics of such biomacromolecule-based constructs. With the goal of increasing information density and structural compl...

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Publication status:
Published

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Publisher copy:
10.1021/jp808239a

Authors


Tumpane, J More by this author
Borjesson, K More by this author
Wilhelmsson, LM More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
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Journal:
JOURNAL OF PHYSICAL CHEMISTRY C
Volume:
113
Issue:
15
Pages:
5941-5946
Publication date:
2009-04-16
DOI:
EISSN:
1932-7455
ISSN:
1932-7447
URN:
uuid:4c24b3f0-7b7b-4c87-8c49-415201db56db
Source identifiers:
400156
Local pid:
pubs:400156
Language:
English

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