- Abstract:
-
AIM: To show that vildagliptin added to metformin is non-inferior to glimepiride in reducing HbA1c levels from baseline over 2 years. METHODS: A randomized, double-blind, active-comparator study of patients with type 2 diabetes mellitus inadequately controlled (HbA1c 6.5-8.5%) by metformin monotherapy. Patients received vildagliptin (50 mg twice daily) or glimepiride (up to 6 mg/day) added to metformin. RESULTS: In all, 3118 patients were randomized (vildagliptin, n = 1562; glimepiride, n = ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1111/j.1463-1326.2010.01233.x
-
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- Journal:
- Diabetes, obesity and metabolism
- Volume:
- 12
- Issue:
- 9
- Pages:
- 780-789
- Publication date:
- 2010-09-05
- DOI:
- EISSN:
-
1463-1326
- ISSN:
-
1462-8902
- URN:
-
uuid:4c2486e6-d6d2-4a5b-a81b-4fa7534a340e
- Source identifiers:
-
72821
- Local pid:
- pubs:72821
- Language:
- English
- Keywords:
- Copyright date:
- 2010
Journal article
Vildagliptin add-on to metformin produces similar efficacy and reduced hypoglycaemic risk compared with glimepiride, with no weight gain: results from a 2-year study.
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