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Journal article

MiR-15a/miR-16-1 expression inversely correlates with cyclin D1 levels in Men1 pituitary NETs

Abstract:

Multiple Endocrine Neoplasia type 1 (MEN1) is an autosomal dominant disorder characterised by the combined occurrence of parathyroid, pituitary and pancreatic islet tumours, and is due to mutations of the MEN1 gene, which encodes the tumour suppressor protein menin. Menin has multiple roles in genome stability, transcription, cell division and proliferation, but its mechanistic roles in tumourigenesis remain to be fully elucidated. MicroRNAs (miRNA) are non-coding single stranded RNAs that po...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1530/JOE-18-0278

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Subgroup:
OCDEM
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Subgroup:
OCDEM
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Subgroup:
OCDEM
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Subgroup:
OCDEM
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Subgroup:
OCDEM
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Publisher:
BioScientifica Publisher's website
Journal:
Journal of Endocrinology Journal website
Volume:
240
Issue:
1
Pages:
41–50
Publication date:
2018-09-01
Acceptance date:
2018-09-28
DOI:
ISSN:
0022-0795 and 1479-6805
Pubs id:
pubs:935314
URN:
uri:4c18bd52-2d9e-4a10-b281-69652a8c96ce
UUID:
uuid:4c18bd52-2d9e-4a10-b281-69652a8c96ce
Local pid:
pubs:935314

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