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Mapping of the mouse homologue of the Wilson disease gene to mouse chromosome 8.

Abstract:

ATP7B, the gene altered in Wilson disease (WD) patients, lies in a block of homology shared between human chromosome 13q14 and the central region of mouse chromosome 14. However, we have mapped the murine homologue of ATP7B (Atp7b) to mouse chromosome 8 by somatic cell hybrid analysis. Analysis of 80 interspecific backcross offspring was used to position Atp7b close to D8Mit3 and another ATPase locus, Atp4b, on mouse chromosome 8. ATP4B lies in 13q34 and is separated from ATP7B by several loc...

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Publication status:
Published

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Publisher copy:
10.1006/geno.1995.1191

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
Journal:
Genomics
Volume:
28
Issue:
3
Pages:
573-575
Publication date:
1995-08-01
DOI:
EISSN:
1089-8646
ISSN:
0888-7543
Source identifiers:
167198
Language:
English
Keywords:
Pubs id:
pubs:167198
UUID:
uuid:4bf542b2-65d9-443a-b96f-e2fff17d510c
Local pid:
pubs:167198
Deposit date:
2012-12-19

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