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Journal article

Airway inflammation in patients with asthma with high-fixed or low-fixed plus as-needed budesonide/formoterol.

Abstract:

BACKGROUND: Budesonide/formoterol maintenance and reliever therapy maintains asthma control and reduces exacerbation frequency compared with higher fixed-dose combination regimens. Its effects on eosinophilic airway inflammation and structure are unknown. OBJECTIVE: We sought to compare the effects of budesonide/formoterol 200/6 microg twice daily plus as-needed with budesonide/formoterol 800/12 microg twice daily on airway eosinophils and remodeling. METHODS: This 52-week, parallel-group, r...

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Publisher copy:
10.1016/j.jaci.2009.02.034

Authors


Pavord, ID More by this author
Jeffery, PK More by this author
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Journal:
The Journal of allergy and clinical immunology
Volume:
123
Issue:
5
Pages:
1083-1089.e7
Publication date:
2009-05-05
DOI:
EISSN:
1097-6825
ISSN:
0091-6749
URN:
uuid:4be678a1-737f-4e70-8e93-b7ea07391b6f
Source identifiers:
423879
Local pid:
pubs:423879

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