Journal article icon

Journal article

Regional brain atrophy development is related to specific aspects of clinical dysfunction in multiple sclerosis.

Abstract:

Brain atrophy in multiple sclerosis (MS) is thought to reflect irreversible tissue damage leading to persistent clinical deficit. Little is known about the rate of atrophy in specific brain regions in relation to specific clinical deficits. We determined the displacement of the brain surface between two T1-weighted MRI images obtained at baseline and after a median follow-up time of 2.2 years for 79 recently diagnosed, mildly disabled MS patients. Voxel- and cluster-wise permutation-based sta...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Jasperse, B More by this author
Vrenken, H More by this author
Sanz-Arigita, E More by this author
de Groot, V More by this author
Expand authors...
Journal:
NeuroImage
Volume:
38
Issue:
3
Pages:
529-537
Publication date:
2007-11-05
DOI:
EISSN:
1095-9572
ISSN:
1053-8119
URN:
uuid:4be0dbbe-5ec1-4d8d-a1df-6b6d74a8f2dd
Source identifiers:
116786
Local pid:
pubs:116786

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP