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Thesis

Mathematical modelling for tendon tissue engineering in a humanoid robotic bioreactor

Abstract:

Tendon tissue engineering aims to grow functional tissue in vitro. Tissue is grown in bioreactors which regulate the biochemical and mechanical environment of the growing cells. This thesis develops mathematical models motivated by the Humanoid Robotic Bioreactor under development at the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences. Cells grow on a scaffold consisting of many aligned, flexible strings, surrounded by cell media. The focus of this work is mo...

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Division:
MPLS
Department:
Mathematical Institute
Role:
Author

Contributors

Role:
Supervisor
Institution:
University of Oxford
Division:
MPLS
Department:
Mathematical Institute
Role:
Supervisor
Institution:
University of Oxford
Division:
MPLS
Department:
Mathematical Institute
Role:
Supervisor
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Supervisor
ORCID:
0000-0003-1192-6362
Institution:
University of Oxford
Division:
MPLS
Department:
Mathematical Institute
Role:
Examiner
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Name:
Biotechnology and Biological Sciences Research Council
Funder identifier:
http://dx.doi.org/10.13039/501100000268
Grant:
BB/M011224/1
Programme:
Interdisciplinary Bioscience DTP
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
DOI:
Language:
English
Keywords:
Subjects:
Deposit date:
2023-05-08

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