- Abstract:
-
Macrophages incubated with soluble antigens for 1-4 days release factors capable of inducing T helper cells. The nature and some of the properties of this genetically related macrophage factor (GRF) were investigated. By use of immunoadsorbents, GRF was shown to contain I region-coded products (Ia antigens) linked to a small antigenic fragment. The genes coding for the Ia antigens detectable in GRF lie in the I region of the H-2 complex. GRF does not react with anti-immunoglobulin, anti-C3 or...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1002/eji.1830060512
-
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- Journal:
- European journal of immunology
- Volume:
- 6
- Issue:
- 5
- Pages:
- 365-372
- Publication date:
- 1976-05-05
- DOI:
- EISSN:
-
1521-4141
- ISSN:
-
0014-2980
- URN:
-
uuid:4bbd81fc-7849-48b2-ba0f-074615a6a9ae
- Source identifiers:
-
481860
- Local pid:
- pubs:481860
- Copyright date:
- 1976
Journal article
Role of macrophages in the generation of T helper cells. IV. Nature of genetically related factor derived from macrophages incubated with soluble antigens.
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