Journal article
Identification of targets of CD8⁺ T cell responses to malaria liver stages by genome-wide epitope profiling.
- Abstract:
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CD8⁺ T cells mediate immunity against Plasmodium liver stages. However, the paucity of parasite-specific epitopes of CD8⁺ T cells has limited our current understanding of the mechanisms influencing the generation, maintenance and efficiency of these responses. To identify antigenic epitopes in a stringent murine malaria immunisation model, we performed a systematic profiling of H(2b)-restricted peptides predicted from genome-wide analysis. We describe the identification of Plasmodium berghei ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 2.5MB)
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- Publisher copy:
- 10.1371/journal.ppat.1003303
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Authors
Funding
+ National Institute for Health Research Oxford Biomedical Research Centre
More from this funder
Funding agency for:
Hill, A
Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS pathogens Journal website
- Volume:
- 9
- Issue:
- 5
- Pages:
- e1003303
- Publication date:
- 2013-05-01
- DOI:
- EISSN:
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1553-7374
- ISSN:
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1553-7366
- Source identifiers:
-
405857
Item Description
- Language:
- English
- Keywords:
- UUID:
-
uuid:4b8af258-9f14-40ad-8115-c6d841cafd4d
- Local pid:
- pubs:405857
- Deposit date:
- 2013-11-17
Terms of use
- Copyright holder:
- Hafalla et al
- Copyright date:
- 2013
- Notes:
- © 2013 Hafalla et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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