- Abstract:
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CD8⁺ T cells mediate immunity against Plasmodium liver stages. However, the paucity of parasite-specific epitopes of CD8⁺ T cells has limited our current understanding of the mechanisms influencing the generation, maintenance and efficiency of these responses. To identify antigenic epitopes in a stringent murine malaria immunisation model, we performed a systematic profiling of H(2b)-restricted peptides predicted from genome-wide analysis. We describe the identification of Plasmodium berghei ...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 2.5MB)
-
- Publisher copy:
- 10.1371/journal.ppat.1003303
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- Funding agency for:
- Hill, AVS
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS pathogens Journal website
- Volume:
- 9
- Issue:
- 5
- Pages:
- e1003303
- Publication date:
- 2013-05-05
- DOI:
- EISSN:
-
1553-7374
- ISSN:
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1553-7366
- URN:
-
uuid:4b8af258-9f14-40ad-8115-c6d841cafd4d
- Source identifiers:
-
405857
- Local pid:
- pubs:405857
- Copyright holder:
- Hafalla et al.
- Copyright date:
- 2013
- Notes:
- © 2013 Hafalla et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Journal article
Identification of targets of CD8⁺ T cell responses to malaria liver stages by genome-wide epitope profiling.
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+ National Institute for Health Research Oxford Biomedical Research Centre
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