Journal article
Inborn and acquired metabolic defects in cancer.
- Abstract:
-
The observation that altered metabolism is the fundamental cause of cancer was made by Otto Warburg nearly a century ago. However, the subsequent identification of oncogenes and tumor suppressor genes has displaced Warburg's theory pointing towards genetic aberrations as the underlining cause of cancer. Nevertheless, in the last decade, cancer-associated mutations have been identified in genes coding for tricarboxylic acid cycle (TCA cycle, also known as Krebs cycle) and closely related enzym...
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- Publication status:
- Published
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- Publisher copy:
- 10.1007/s00109-011-0728-4
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Authors
Bibliographic Details
- Journal:
- Journal of molecular medicine (Berlin, Germany)
- Volume:
- 89
- Issue:
- 3
- Pages:
- 213-220
- Publication date:
- 2011-03-01
- DOI:
- EISSN:
-
1432-1440
- ISSN:
-
0946-2716
- Source identifiers:
-
149851
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:149851
- UUID:
-
uuid:4b88c976-1af8-474c-a31d-f7ee028554b3
- Local pid:
- pubs:149851
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2011
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