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A randomized study of the influence of perfusion technique and pH management strategy in 316 patients undergoing coronary artery bypass surgery. II. Neurologic and cognitive outcomes.

Abstract:

This double-blind, randomized comparison of pulsatile or nonpulsatile perfusion and alpha-stat or pH-stat management during cardiopulmonary bypass was designed to assess postoperative central nervous system outcomes. METHODS: Neurologic and cognitive testing was conducted before the operation and 7 days and 2 months after the operation in 316 patients having coronary artery bypass and in a reference cohort of 40 patients having major vascular and thoracic operations. RESULTS: As detailed in p...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Stroke and Geratology
Role:
Author
Journal:
The Journal of thoracic and cardiovascular surgery
Volume:
110
Issue:
2
Pages:
349-362
Publication date:
1995-08-05
DOI:
EISSN:
1097-685X
ISSN:
0022-5223
URN:
uuid:4b8408d4-df6d-4046-b92e-0b61ea838006
Source identifiers:
80180
Local pid:
pubs:80180

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