- Abstract:
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Malaria, caused by the apicomplexan parasite Plasmodium, threatens 40% of the world's population. Transmission between vertebrate and insect hosts depends on the sexual stages of the life-cycle. The male gamete of Plasmodium parasite is the only developmental stage that possesses a flagellum. Very little is known about the identity or function of proteins in the parasite's flagellar biology. Here, we characterise a Plasmodium PF16 homologue using reverse genetics in the mouse malaria parasite...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
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(pdf, 4.1MB)
-
- Publisher copy:
- 10.1371/journal.pone.0012901
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- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PloS one Journal website
- Volume:
- 5
- Issue:
- 9
- Pages:
- Article: e12901
- Publication date:
- 2010-01-01
- DOI:
- EISSN:
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1932-6203
- ISSN:
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1932-6203
- URN:
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uuid:4b8404f4-e560-45c1-be96-faafd8c272a9
- Source identifiers:
-
149521
- Local pid:
- pubs:149521
- Copyright holder:
- Straschil et al.
- Copyright date:
- 2010
- Notes:
- Copyright 2010 Straschil et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Journal article
The Armadillo repeat protein PF16 is essential for flagellar structure and function in Plasmodium male gametes.
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Medical Research Council
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Wellcome Trust
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Leverhulme Trust
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BioMalPar
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