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Journal article

The Armadillo repeat protein PF16 is essential for flagellar structure and function in Plasmodium male gametes.

Abstract:

Malaria, caused by the apicomplexan parasite Plasmodium, threatens 40% of the world's population. Transmission between vertebrate and insect hosts depends on the sexual stages of the life-cycle. The male gamete of Plasmodium parasite is the only developmental stage that possesses a flagellum. Very little is known about the identity or function of proteins in the parasite's flagellar biology. Here, we characterise a Plasmodium PF16 homologue using reverse genetics in the mouse malaria parasite...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pone.0012901

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Lab Sciences
Role:
Author
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Funding agency for:
Ferguson, D
Medical Research Council More from this funder
Wellcome Trust More from this funder
Leverhulme Trust More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PloS one Journal website
Volume:
5
Issue:
9
Article number:
e12901
Publication date:
2010-01-01
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
Source identifiers:
149521
Language:
English
Keywords:
UUID:
uuid:4b8404f4-e560-45c1-be96-faafd8c272a9
Local pid:
pubs:149521
Deposit date:
2012-12-19

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