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Journal article

Anti-microbial peptide gene expression during oral vaccination: analysis of a randomized controlled trial

Abstract:

We have observed previously that micronutrient supplementation ameliorated suppression of α-defensin expression during diarrhoea. However, how interactions between anti-microbial peptide (AMP) expression and diarrhoeal disease are altered by micronutrient supplementation remain unclear. Using oral vaccination as a model of intestinal infection, we measured changes in AMP expression during multiple micronutrient supplementation. In the first part, volunteers underwent duodenal jejunal biopsy b...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1111/cei.12848

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Institution:
University of Oxford
Department:
Oxford, MSD, NDM, Tropical Medicine
Role:
Author
Publisher:
Wiley Publisher's website
Journal:
Clinical and Experimental Immunology Journal website
Volume:
186
Issue:
2
Pages:
205-213
Publication date:
2016-08-29
Acceptance date:
2016-07-25
DOI:
EISSN:
1365-2249
ISSN:
0009-9104
Pubs id:
pubs:681942
URN:
uri:4b43f454-0bfe-4689-94b4-2015b5658767
UUID:
uuid:4b43f454-0bfe-4689-94b4-2015b5658767
Local pid:
pubs:681942
Paper number:
2

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