- Abstract:
-
We have studied exercise metabolism in vivo in the mdx mouse model of Duchenne muscular dystrophy with 31P-nuclear magnetic resonance spectroscopy. Intracellular pH, ratios of phosphocreatine (PCr) to ATP and PCr to inorganic phosphate (P(i)) expressed as PCr/ATP and PCr/(PCr+P(i)) as well as tension generated at the Achilles tendon were measured during sciatic nerve stimulation. Tension was similar between the mdx and control strain C57Bl/10ScSn at 10 Hz stimulation but slightly higher than ...
Expand abstract - Publisher copy:
- 10.1016/0022-510X(92)90272-M
-
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- Journal:
- J Neurol Sci
- Volume:
- 113
- Issue:
- 1
- Pages:
- 108-113
- Publication date:
- 1992-11-05
- DOI:
- ISSN:
-
0022-510X
- URN:
-
uuid:4b37276d-f9fa-4520-b96e-cc5a2f9da376
- Source identifiers:
-
376242
- Local pid:
- pubs:376242
- Copyright date:
- 1992
Journal article
A 31P-NMR study of muscle exercise metabolism in mdx mice: evidence for abnormal pH regulation.
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