Gene regulatory networks: a coarse-grained, equation-free approach to multiscale computation.
We present computer-assisted methods for analyzing stochastic models of gene regulatory networks. The main idea that underlies this equation-free analysis is the design and execution of appropriately initialized short bursts of stochastic simulations; the results of these are processed to estimate coarse-grained quantities of interest, such as mesoscopic transport coefficients. In particular, using a simple model of a genetic toggle switch, we illustrate the computation of an effective free e...Expand abstract
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- 33 pages, submitted to The Journal of Chemical Physics
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