Journal article
The use of genome-wide eQTL associations in lymphoblastoid cell lines to identify novel genetic pathways involved in complex traits.
- Abstract:
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The integrated analysis of genotypic and expression data for association with complex traits could identify novel genetic pathways involved in complex traits. We profiled 19,573 expression probes in Epstein-Barr virus-transformed lymphoblastoid cell lines (LCLs) from 299 twins and correlated these with 44 quantitative traits (QTs). For 939 expressed probes correlating with more than one QT, we investigated the presence of eQTL associations in three datasets of 57 CEU HapMap founders and 86 un...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 887.7KB, Terms of use)
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- Publisher copy:
- 10.1371/journal.pone.0022070
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Funding
Bibliographic Details
- Publisher:
- Public Library of Science
- Journal:
- PloS one More from this journal
- Volume:
- 6
- Issue:
- 7
- Article number:
- e22070
- Publication date:
- 2011-01-01
- DOI:
- EISSN:
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1932-6203
- ISSN:
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1932-6203
Item Description
- Language:
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English
- Keywords:
-
- UUID:
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uuid:4af8403d-8b2c-4129-9e0c-95f35946615e
- Local pid:
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pubs:167537
- Source identifiers:
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167537
- Deposit date:
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2012-12-19
Terms of use
- Copyright holder:
- Min et al
- Copyright date:
- 2011
- Notes:
-
Copyright 2011 Min et al.
This is an open-access article distributed under the terms of the Creative Commons Attribution License,
which permits unrestricted use, distribution, and reproduction in any medium, provided the
original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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