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Journal article

Calcium binding activity of the epidermal growth factor-like domains of the apicomplexan microneme protein EtMIC4.

Abstract:

Microneme proteins are secreted from apicomplexan parasites during invasion of host cells and they play crucial roles in parasite-host cell adhesion. EtMIC4 is a 240 kDa transmembrane protein from Eimeria tenella that contains 31 tandemly arranged epidermal growth factor (EGF), like repeats within its extracellular domain. The majority of these repeats have calcium binding (cb) consensus sequences. Little is known about cbEGFs in apicomplexan parasites but their presence in microneme proteins...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Role:
Author
Journal:
Molecular and biochemical parasitology
Volume:
143
Issue:
2
Pages:
192-199
Publication date:
2005-10-05
DOI:
EISSN:
1872-9428
ISSN:
0166-6851
URN:
uuid:4af73f8d-fd29-4f0c-a800-24e14dd00077
Source identifiers:
100006
Local pid:
pubs:100006

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