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Journal article

Measurement of TIMP-3 expression and Bruch's membrane thickness in human macula.

Abstract:

An increase or accumulation in tissue inhibitor of matrix metalloproteinases-3 (TIMP-3) protein in Bruch's membrane with ageing in normal eyes, and in age related macular degeneration (AMD) has been previously demonstrated. The purpose of this study was to determine whether the expression of TIMP-3 mRNA increases with age, and to define any relationship between altered expression and Bruch's membrane thickness. Normal eyes were obtained from 30 donors (age range 15-90 years). Full-thickness 8...

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Publisher copy:
10.1006/exer.2001.1089

Authors


Journal:
Experimental eye research
Volume:
73
Issue:
6
Pages:
851-858
Publication date:
2001-12-05
DOI:
EISSN:
1096-0007
ISSN:
0014-4835
URN:
uuid:4ac04137-41c4-4680-95e3-1e020516747e
Source identifiers:
254175
Local pid:
pubs:254175

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